Figure 2.

The effects of JTW on the duration of immobility in the forced swimming (a) and tail suspension (b) tests. Mice were administered vehicle, JTW (3.3 and 6.6 mg/kg) or imipramine (10 mg/kg) once daily for 14 consecutive days. On the last day, mice were subjected to the behavioral tests after 30 min drug administration. Values are the mean ± S.E.M. with 6 mice in each group. Compared with vehicle-treated ovariectomized mice, ^#p < 0.05; compared with vehicle-treated ovariectomized mice subjected to chronic unpredictable stress, ^∗p < 0.05 and ^∗∗p < 0.01.