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. 2020 Sep 26;12:116. doi: 10.1186/s13195-020-00687-2

Table 2.

Dietary intake and energy expenditure according to diagnosis group

Controls MCI AD dementia p value
Dietary intake
FFQ, N 96 52 71
  Energy (kcal/day) 2022 ± 61 2172 ± 80 1991 ± 71 0.196
  Protein (EN%) 15.2 ± 0.3 15.5 ± 0.4 15.1 ± 0.3 0.688
  Carbohydrate (EN%) 41.4 ± 0.7 41.2 ± 1.0 40.2 ± 0.8 0.572
  Fat (EN%) 34.5 ± 0.6 34.5 ± 0.8 34.2 ± 0.7 0.948
3-day food diary, N 40 22 30
  Energy (kcal/day) 2081 ± 71 2042 ± 93 2000 ± 83 0.787
  Protein (EN%) 17.0 ± 0.6 15.8 ± 0.7 15.2 ± 0.6 0.079
  Carbohydrate (EN%) 40.5 ± 1.2 42.6 ± 1.5 42.0 ± 1.4 0.540
  Fat (EN%) 35.0 ± 1.0 36.0 ± 1.3 37.1 ± 1.2 0.424
Energy expenditure
Resting energy expenditure, N 38 22 28
Fasted (hours) 14.1 ± 0.3 14.6 ± 0.4 13.7 ± 0.4 0.308
  Oxygen consumption (ml/min) 229 ± 5 257 ± 7a 248 ± 6 0.007
  Carbon dioxide production (ml/min) 184 ± 4 201 ± 6 188 ± 5 0.076
  REE (kcal/day) 1578 ± 34 1762 ± 48a 1691 ± 43a 0.009
  REE (kcal/kg FFM) 30.8 ± 0.7 34.5 ± 0.9a 33.2 ± 0.8 0.007
Physical activity, N 11 10 10
  Wear time (min/day) 881.9 ± 23.1 868.5 ± 26.4 869.7 ± 24.5 0.911
  Total (min) 328.5 ± 28.3 358.5 ± 32.3 302.8 ± 30.0 0.505
  Light (min) 305.3 ± 26.4 322.9 ± 30.1 272.0 ± 28.0 0.486
  Low light (min) 223.8 ± 16.5 222.5 ± 19.8 201.5 ± 17.6 0.613
  High light (min) 81.5 ± 15.4 100.4 ± 17.6 70.4 ± 16.3 0.514
  Moderate to vigorous (min) 15.0 [2.9–45.1] 22.7 [4.5–51.0] 25.3 [12.6–54.2] 0.461

Data in mean ± SE; median [interquartile range]; intake: ANOVA adjusted for age, sex, education, and BMI; REE: ANOVA post-hoc Bonferroni adjusted for age, sex, education, and FFM; physical activity: ANOVA adjusted for age, sex, and education

AD Alzheimer’s disease, MCI mild cognitive impairment, FFQ food frequency questionnaire, EN% energy percentage, FFM fat free mass, REE resting energy expenditure

aSignificantly different from controls upon post-hoc testing