. 2020 Sep 24;8:e10008. doi: 10.7717/peerj.10008

Table 3. Correlation analysis of the clinical characteristics and the twenty-three gene signature in LUAD.

Characteristics	TCGA training cohort (n = 445)					GSE30219 testing cohort (n = 83)					GSE72094 testing cohort (n = 393)
	n	Mean (rick score)	SD	t	P	n	Mean (rick score)	SD	t	P	n	Mean (rick score)	SD	t	P
Age(years)
<68	247	0.765	0.64	−0.164	0.87	23	0.543	0.346	−0.088	0.931	153	1.253	0.93	−0.524	0.600
≥68	198	0.775	0.663	60	0.55	0.272	240	1.305	1.04
Gender
Female	244	0.702	0.611	−2.393	0.017	19	0.535	0.357	−0.183	0.856	219	1.203	1.012	−1.850	0.065
Male	201	0.851	0.686			64	0.552	0.274			174	1.389	0.972
TNM stage
Stage I+II	348	0.68	0.584	−4.822	<0.001	60	0.456	0.235	−6.598	<0.001	320	1.166	0.842	−3.771	<0.001
Stage III+IV	97	1.083	0.765			23	0.875	0.239			73	1.805	1.392
T
T1+2	387	0.716	0.595	−3.5	0.001	73	0.528	0.299	−2.479	0.024	–	–	–	–	–
T3+4	58	1.125	0.86			10	0.697	0.185	–	–	–
N
N0	292	0.71	0.639	−2.629	0.009	71	0.502	0.276	−4.03	0.001	–	–	–	–	–
N1-3	153	0.881	0.657			12	0.817	0.245			–	–	–
M
M0	403	0.742	0.64	−2.577	0.013	67	0.468	0.241	−5.959	<0.001	–	–	–	–	–
M1	42	1.028	0.689	16	0.881	0.251		–	–	–

Notes.