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. 2020 Sep 22;12:8773–8785. doi: 10.2147/CMAR.S260537

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© 2020 Liu et al.

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PVT1 silence inhibits the progression of CRC cells through regulating miR-106b-5p expression. (A and B) The expression of miR-106b-5p was measured using qRT-PCR to verify the transfection efficiency after transfection with sh-NC, sh-PVT1, sh-PVT1 + anti-miR-NC or sh-PVT1 + anti-miR-106b-5p, respectively. (C and D) The proliferation activity was examined by MTT assay in HCT116 and HT29 cells. (E and F) Transwell assay was used to demonstrate the migration and invasion abilities of HCT116 and HT29 cells. *P<0.05.