Table 3.
Effect on GI Secretion, Total Acidity and pH on Pylorus Ligation-Induced Ulcerated Rat
| Group | VoGJ | TA(mEq/L) | % Red TA | pH |
|---|---|---|---|---|
| Solvent 10 ml/kg | 4.75 ± 0.075 | 56.33 ± 0.22 | 0.00 | 1.88 ± 0.13 |
| Omp 20 mg/kg | 1.83 ± 0.05a3 | 16.65 ± 0.304a3 | 70.44 | 6.19 ± 0.13a3 |
| RN 100 mg/kg | 2.10 ± 0.11a3 | 17.78 ± 0.19a3 | 68.44 | 5.97 ± 0.14a3 |
| RN 200 mg/kg | 2.04 ± 0.12a3 | 17.50 ± 0.43a3 | 68.93 | 6.03 ± 0.19a3 |
| RN 400 mg/kg | 1.93 ± 0.05a3 | 16.73 ± 0.15a3 | 70.3 | 6.09 ± 0.10a3 |
Notes: Each value represents mean ± SEM; n=6; a: against negative control; 3: p<0.001; Omp: Omeprazole, SEM: standard error of the mean; RN100: Rumex nepalensis 100 mg/kg, RN200: Rumex nepalensis 200 mg/kg, RN400: Rumex nepalensis 400 mg/kg, VoGJ: volume of gastric juice, %Red V: percentage reduction in volume of gastric juice, TA: total acidity, % Red TA: percentage reduction in total acidity.