Table 7.
Rumex nepalensis Root Solvent Fractions Effect on Ulcer Score and Ulcer Index in Pylorus Ligation-Induced Ulcerated Rats
| Group | US | % Red US | UI | % Red UI |
|---|---|---|---|---|
| Solvent 10 mg/kg | 91.17 ± 1.94 | 0.00 | 24.82 ± 0.23 | 0.00 |
| Omp 20 mg/kg | 5.67 ± 1.89a3 | 93.78 | 7.47 ± 2.36a3 | 69.9 |
| CF 100 mg/kg | 87.00 ± 2.94b3 | 4.57 | 24.19 ± 0.37b3 | 2.54 |
| CF 200 mg/kg | 84.08 ± 4.20b3 | 7.78 | 23.73 ± 0.69b3 | 4.4 |
| CF 400 mg/kg | 80.08 ± 1.58b3 | 12.16 | 22.69 ± 0.21b3 | 8.6 |
| EF 100 mg/kg | 9.92 ± 1.03a3 | 89.12 | 11.6 ± 0.23a3 | 53.26 |
| EF 200 mg/kg | 8.33 ± 1.68a3 | 90.86 | 9.58 ± 1.92a3 | 61.40 |
| EF 400 mg/kg | 5.92 ± 1.89a3 | 93.51 | 7.63 ± 2.41a3 | 69.26 |
| AF 100 mg/kg | 22.17 ± 0.90a3b2 | 75.68 | 13.48 ± 0.15a3 | 45.69 |
| AF 200 mg/kg | 17.33 ± 3.51a3b1 | 80.99 | 11.02 ± 2.20a3 | 55.60 |
| AF 400 mg/kg | 13.33 ± 2.69a3 | 85.38 | 10.37± 2.04a3 | 58.23 |
Notes: Each value represents mean ± SEM; n=6; CF: chloroform fraction, EF: ethyl acetate fraction, AF: aqueous fraction, a: against negative control, b: against standard (Omp20); 1: p<0.05, 2: p<0.01, 3: p<0.001, Omp20: Omeprazole 20 mg/kg, SEM: standard error of the mean.