Table 8.

Solvent Fractions Antisecretory Effect on Pylorus Ligation-Induced Ulcer

Group	VoGJ (mL)	% Red V	TA(mEq/L)
Solvent 10 mL/kg	6.22 ± 0.11	64.03 ± 0.6	1.7 ± 0.06
Omp 20 mg/kg	1.45 ± 0.10a3	8.55 ± 0.26a3	6.73 ± 0.09a3
CF 100 mg/kg	6.08 ± 0.27b3	61.14 ± 2.28b3	1.80 ± 0.07b3
CF 200 mg/kg	5.94 ± 0.38b3	59.43 ± 1.28b3	1.91 ± 0.18b3
CF 400 mg/kg	5.26 ± 0.23a1b3	57.83 ± 2.43a1b3	2.24 ± 0.06a1b3
EF 100 mg/kg	1.83 ± 0.07a3	9.91 ± 0.20a3	6.25 ± 0.10a3
EF 200 mg/kg	1.81 ± 0.05a3	9.63 ± 0.08a3	6.36 ± 0.09a3
EF 400 mg/kg	1.51 ± 0.13a3	9.04 ± 0.53a3	6.54 ± 0.02a3
AF 100 mg/kg	1.80 ± 0.05a3	10.04 ± 0.30a3	6.19 ± 0.12a3b1
AF 200 mg/kg	1.78 ± 0.06a3	9.41 ± 0.26a3	6.30 ± 0.17a3
AF 400 mg/kg	1.64 ± 0.10a3	8.93 ± 0.28a3	6.41 ± 0.10a3

Notes: Each value represents mean ± SEM; n=6; CF: chloroform fraction, EF: ethyl acetate fraction, AF: aqueous fraction, a: against negative control; b: against standard (Omp20), 1: p<0.05, 2: p<0.01, 3: p<0.001, Omp20: Omeprazole 20 mg/kg, DW10: SEM: standard error of the mean, VoGJ: volume of gastric juice secretions, %Red V: percentage reduction in volume of gastric juice, TA: total acidity, %Red TA: percentage reduction in total acidity of gastric secretions.