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. 2020 Sep 23;13:9407–9417. doi: 10.2147/OTT.S257271

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© 2020 Cao et al.

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Longitudinal serum (A) VEGF and (B) MMP-9 in individual patients. Serum concentrations of VEGF and MMP-9 were plotted on the Y-axis and sampling time after therapy were plotted on the X-axis. Each dot represents a sample and different time points for the same patient is linked by a line.

Abbreviations: EGFR−, EGFR-negative patients with HCC; EGRF+, EGFR-positive patients with HCC; E group, patients treated with adriamycin and its isomers regimen are included; P group, patients treated with platinum regimen are included; and O group, patients treated with other regimens are included.