Table 2.

Relation of Serum VEGF and MMP9 to Clinicopathological Characteristics of 139 Patients with HCC (Concentration Unit: VEGF, Pg/mL; MMP-9, Ng/mL)

Group	EGFR		N	VEGF Mean (SD)	P value	MMP-9 Mean (SD)	P value
Gender	+	Male	49	176.0(144.5)		1020.4(443.4)
		Female	10	160.4(84.2)	0.744	987.3(370.3)	0.826
	–	Male	64	157.9(122.2)		1007.5(847.2)
		Female	16	136.6(63.8)	0.505	665.8(343.7)	0.119
Age	+	<50yr	14	175.0(94.1)		1089.6(515.9)
		50–70yr	43	178.0(148.6)		981.7(395.8)
		>70yr	2	62.0(8.5)	0.505	1202.0(666.1)	0.596
	–	<50yr	22	130.9(81.0)		1110.0(929.1)
		50–70yr	47	165.8(130.2)		922.9(776.3)
		>70yr	11	147.1(84.4)	0.485	667.4(341.9)	0.306
Stage	+	I	4	125.0(86.3)		770.5(313.5)
		II	19	162.4(177.1)		908.1(398.9)
		III	25	170.1(90.2)		1215.6(449.9)
		IV	11	217.3(158.8)	0.626	831.5(287.9)	0.015
	–	I	18	185.5(175.6)		682.5(403.6)
		II	40	151.3(92.0)		841.6(320.2)
		III	10	139.9(88.9)		1273.5(1351.0)
		IV	12	124.9(68.8)	0.506	1370.9(1360.9)	0.142
Metastasis	+	Yes	13	181.5(160.7)		804.3(308.5)
		No	46	171.0(129.7)	0.808	1074.3(442.2)	0.044
	–	Yes	11	108.2(34.7)		715.5(294.3)
		No	69	160.9(119.4)	0.152	974.9(831.2)	0.311
Recurrence	+	Yes	24	146.1(117.1)		1157.5(522.0)
		No	35	192.1(145.8)	0.204	916.9(324.8)	0.033
	–	Yes	34	146.8(137.1)		1113.6(1110.0)
		No	46	158.7(92.5)	0.644	810.3(366.1)	0.087
HBsAg	+	+	27	180.5(114.8)		1061.3(489.8)
		–	32	167.3(152.7)	0.713	975.5(373.9)	0.449
	–	+	52	156.0(123.5)		874.9(742.0)
		–	28	149.1(92.1)	0.797	1058.5(856.2)	0.320
Differentiation	+	High	4	125.0(86.3)		770.5(313.5)
		Moderate	38	176.0(139.0)		1119.3(461.1)
		Low	17	178.8(141.6)	0.766	838.6(289.0)	0.038
	–	High	19	182.9(171.0)		699.1(398.8)
		Moderate	43	151.5(87.9)		950.7(705.6)
		Low	18	127.8(87.0)	0.331	1165.1(1155.3)	0.194