Table 3.
Changes of Serum Inflammatory Factors Levels Before and After Treatment in Two Groups
| Parameter | hs-CRP (mmol/L) | IL-6 (pg/mL) | TNF-α (pg/mL) | ICAM-1 (μg/L) | |
|---|---|---|---|---|---|
| Conventional-dose group (n=46) | Before treatment | 8.31±0.81 | 353.51±45.68 | 16.29±4.26 | 567.52±94.15 |
| 8th week of the therapy | 3.33±0.75 a | 130.05±43.78 a | 5.53±1.11 a | 375.87±63.69 a | |
| High-dose group (n=47) | Before treatment | 8.24±0.88 | 366.27±50.43 | 17.10±4.13 | 574.51±85.75 |
| 8th week of the therapy | 2.78±0.96 a,b | 95.62±28.14 a,b | 4.43±0.98 a,b | 316.98±64.22 a,b |
Notes: Data are presented as means±SD. aindicates a significant difference compared before treatment (P< 0.05). bindicates a significant difference compared conventional-dose group (P< 0.05). Paired student’s t test was used before and after treatment, and Wilcoxon test was used between groups.
Abbreviations: hs-CRP, high sensitive C reactive protein; ICAM-1, intercellular cell adhesion molecule-1; IL-6, interleukin-6; TNF-α, tumor necrosis factor α.