Table 3.
Comparison of Mean Monthly Costs of Antimicrobial Administration in the Average Value of USD During the Two Phases of the Study (Pre- and Post-Intervention)
| Antimicrobial Agent | Study Phase | Percent of Change | P-value | |
|---|---|---|---|---|
| Pre-ASP | Post-ASP | |||
| Antifungal | ||||
| Amphotericin | 123,300 | 66,940 | −45.7% | <0.001 |
| Caspofungin | 7000 | 3700 | −47.1% | <0.001 |
| Voriconazole | 11,160 | 4400 | −60.6% | <0.001 |
| Antibacterial (spectrum of activity) | ||||
| Colistin (G−) | 26,312 | 13,500 | −48.7% | <0.001 |
| Linezolid (G+) | 18,100 | 20,170 | +10.3% | 0.002 |
| Carbapenems (G+, G−) | 182,600 | 99,270 | −45.6% | <0.001 |
| Vancomycin (G+) | 69,100 | 46,540 | −32.6% | <0.001 |
| Total | 437,572 | 254,520 | −41.8% | <0.001 |
Abbreviations: ASP, antimicrobial stewardship program; USD, United States dollars.