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. 2020 Jul 26;24(17):10151–10165. doi: 10.1111/jcmm.15625

Figure 3.

Figure 3

Up‐regulated CXXC4 exerts inhibitory effects on the proliferation of gastric cancer cells and activation of T cells by inhibiting the expression of MIR100HG. A, The expression of CXXC4 and MIR100HG measured by RT‐qPCR, n = 3. B, The proliferation of SGC7901 cells detected by CCK‐8 assay, n = 3. C, The proliferative ability of CD3+ T cell and the proportion of activated IFN‐γ+ T cells detected by flow cytometry, n = 3. D, The IFN‐γ cytokine secreted by T cells measured by ELISA, n = 3, *P < .05 oe‐CXXC4 + oe‐NC vs oe‐NC, # P < .05 oe‐CXXC4 + oe‐MIR100HG vs oe‐CXXC4 + oe‐NC. Measurement data were expressed as mean ± SD. Comparisons between two groups in panels A, C and D were analysed by unpaired t test. Comparisons among multiple groups in panels A, C and D were analysed using one‐way ANOVA, followed by Bonferroni's post hoc test. The data at different time points in panel B were analysed by the repeated measures ANOVA followed by Bonferroni's post hoc test. The experiment was repeated three times independently