TABLE 1.
The age‐standardized incidence rate (ASIR) and age‐standardized mortality rate (ASMR) in 1990 and 2017, and their temporal trends from 1990 to 2017
| Characteristics | ASIR/incidence rate (95% UI) | ASMR/death rate (95% UI) | EAPC (95% CI) | |||
|---|---|---|---|---|---|---|
| Per 100 000 in 1990 | Per 100 000 in 2017 | Per 100 000 in 1990 | Per 100 000 in 2017 | ASIR/incidence rate（1990‐2017) | ASMR/death rate (1990‐2017) | |
| Overall | 7.57 (7.33‐7.85) | 5.90 (5.74‐6.06) | 7.72 (7.48‐8.01) | 5.48 (5.34‐5.63) | −1.21 (−1.41 to −1.01) | −1.57 (−1.79 to −1.36) |
| Sex | ||||||
| Male | 10.90 (10.54‐11.33) | 8.87 (8.55‐9.16) | 11.12 (10.74‐11.56) | 8.43 (8.15‐8.70) | −1.02 (−1.21 to −0.84)) | −1.30 (−1.50 to −1.10) |
| Female | 4.69 (4.47‐4.98) | 3.32 (3.17‐3.47) | 4.84 (4.61‐5.16) | 2.93 (2.81‐3.05) | −1.63 (−1.88 to −1.39) | −2.23 (−2.48 to −1.97) |
| Age | ||||||
| 15‐49 years | 1.36 (1.30‐1.44) | 1.04 (1.01‐1.08) | 1.11 (1.06‐1.17) | 0.75 (0.73‐0.77) | −1.74 (−2.14 to −1.35) | −2.25 (−2.67 to −1.84) |
| 50‐69 years | 24.45 (23.66‐25.35) | 17.79 (17.28‐18.31) | 23.45 (22.67‐24.33) | 15.55 (15.13‐16.00) | −1.47 (−1.66 to −1.29) | −1.87 (−2.06 to −1.68) |
| 70 + years | 51.62 (49.94‐53.82) | 45.58 (44.13‐47.03) | 58.90 (56.95‐61.41) | 46.60 (45.57‐47.94) | −0.76 (−0.98 to −0.53) | −1.16 (−1.40 to −0.93) |
| Socio‐demographic index | ||||||
| Low | 5.36 (4.93‐5.78)) | 4.29 (4.04‐4.57) | 5.60 (5.16‐6.05) | 4.54 (4.28‐4.84) | −0.99 (−1.17 to −0.83) | −0.95 (−1.12 to −0.77) |
| Low‐middle | 5.18 (4.86‐5.51) | 4.42 (4.21‐4.67) | 5.40 (5.05‐5.75) | 4.63 (4.41‐4.88) | −0.70 (−0.78 to −0.62) | −0.68 (−0.76 to −0.60) |
| Middle | 11.46 (10.96‐12.05) | 6.89 (6.55‐7.26) | 12.06 (11.52‐12.68) | 6.79 (6.45‐7.13) | −2.18 (−2.44 to −1.91) | −2.42 (−2.71 to −2.14) |
| High‐middle | 10.15 (9.69‐10.64) | 8.10 (7.62‐8.59) | 10.60 (10.12‐11.11) | 7.22 (6.84‐7.63) | −1.24 (−1.51 to −0.96) | −1.86 (−2.16 to −1.56) |
| High | 4.42 (4.38‐4.48) | 4.30 (4.18‐4.42) | 4.14 (4.10‐4.18) | 3.50 (3.42‐3.58) | −0.27 (−0.39 to −0.14) | −0.78 (−0.87 to −0.69) |
| Region | ||||||
| High‐income Asia Pacific | 5.97 (5.87‐6.06) | 5.15 (4.87‐5.41) | 4.60 (4.54‐4.67) | 3.28 (3.14‐3.42) | −0.69 (−0.90 to −0.48) | −1.42 (−1.59 to −1.26) |
| Central Asia | 12.62 (12.32‐12.93) | 5.67 (5.40‐5.93) | 13.28 (12.96‐13.62) | 5.99 (5.71‐6.27) | −3.28 (−3.51 to −3.06) | −3.28 (−3.51 to −3.05) |
| East Asia | 18.92 (18.09‐20.03) | 12.09 (11.51‐12.67) | 20.03 (19.14‐21.19) | 11.09 (10.59‐11.59) | −2.01 (−2.31 to −1.70) | −2.54 (−2.87 to −2.21) |
| South Asia | 4.48 (4.20‐4.76) | 3.93 (3.71‐4.17) | 4.65 (4.35‐4.95) | 4.11 (3.88‐4.36) | −0.69 (−0.83 to −0.55) | −0.66 (−0.80 to −0.53) |
| Southeast Asia | 3.06 (2.74‐3.32) | 2.51 (2.36‐2.69) | 3.22 (2.88‐3.50) | 2.60 (2.45‐2.79) | −0.81 (−0.85 to −0.76) | −0.86 (−0.92 to −0.81) |
| Australasia | 4.51 (4.38‐4.65) | 4.45 (4.03‐4.90) | 4.04 (3.94‐4.15) | 3.77 (3.42‐4.15) | −0.23 (−0.35 to −0.10) | −0.43 (−0.51 to −0.34) |
| Caribbean | 3.61 (3.47‐3.80) | 3.29 (3.02‐3.60) | 3.85 (3.699‐4.04) | 3.40 (3.13‐3.72) | −0.33 (−0.64 to −0.02) | −0.46 (−0.77 to −0.15) |
| Central Europe | 2.94 (2.89‐2.99) | 2.68 (2.58‐2.79) | 2.99 (2.95‐3.05) | 2.73 (2.63‐2.83) | −0.41 (−0.52 to −0.29) | −0.42 (−0.51 to −0.34) |
| Eastern Europe | 3.99 (3.87‐4.12) | 3.46 (3.36‐3.58) | 3.90 (3.81‐3.98) | 2.91 (2.84‐2.995) | −0.89 (−1.18 to −0.60) | −1.51 (−1.78 to −1.24) |
| Western Europe | 4.22 (4.16‐4.29) | 3.99 (3.82‐4.18) | 4.17 (4.12‐4.23) | 3.41 (3.28‐3.54) | −0.35 (−0.43 to −0.27) | −0.89 (−0.96 to −0.82) |
| Andean Latin America | 1.96 (1.86‐2.08) | 1.31 (1.18‐1.43) | 2.13 (2.01‐2.26) | 1.43 (1.29‐1.57) | −1.65 (−1.75 to −1.54) | −1.62 (−1.73 to −1.52) |
| Central Latin America | 2.05 (2.01‐2.09) | 1.38 (1.31‐1.44) | 2.22 (2.19‐2.26) | 1.48 (1.41‐1.54) | −1.76 (−1.90 to −1.61) | −1.81 (−1.95 to −1.66) |
| Southern Latin America | 6.79 (6.62‐6.96) | 4.01 (3.72‐4.41) | 7.32 (7.14‐7.497) | 4.31 (3.99‐4.71) | −2.19 (−2.31 to −2.06) | −2.20 (−2.32 to −2.07) |
| Tropical Latin America | 5.68 (5.57‐5.80) | 4.65 (4.53‐4.76) | 5.95 (5.84‐6.07) | 4.81 (4.70‐4.92) | −0.84 (−0.91 to −0.78) | −0.87 (−0.93 to −0.81) |
| North Africa and Middle East | 2.70 (2.43‐2.98) | 2.18 (2.04‐2.35) | 2.81 (2.53‐3.12) | 2.29 (2.14‐2.48) | −0.83 (−0.95 to −0.71) | −0.77 (−0.90 to −0.65) |
| High‐income North America | 3.61 (3.57‐3.67) | 3.88 (3.77‐4.00) | 3.49 (3.45‐3.54) | 3.47 (3.37‐3.56) | 0.04 (−0.13 to 0.22) | −0.23 (−0.36 to −0.10) |
| Oceania | 2.26 (1.96‐2.61) | 2.21 (1.91‐2.54) | 2.34 (2.03‐2.71) | 2.31 (2.00‐2.64) | −0.03 (−0.07 to 0.01) | 0.002 (−0.04 to 0.04) |
| Central Sub‐Saharan Africa | 10.38 (9.03‐11.899) | 7.26 (6.17‐8.51) | 10.90 (9.46‐12.49) | 7.67 (6.54‐9.01) | −1.62 (−1.79 to −1.44) | −1.58 (−1.75 to −1.41) |
| Eastern Sub‐Saharan Africa | 10.74 (9.799‐11.78) | 7.80 (7.20‐8.57) | 11.41 (10.45‐12.49) | 8.35 (7.72‐9.17) | −1.45 (−1.58 to −1.33) | −1.41 (−1.53 to −1.29) |
| Southern Sub‐Saharan Africa | 12.31 (11.33‐13.37) | 9.96 (9.47‐10.42) | 12.68 (11.68‐13.77) | 10.53 (10.02‐11.02) | −1.26 (−2.07 to −0.44) | −1.13 (−1.93 to −0.33) |
| Western Sub‐Saharan Africa | 2.93 (2.57‐3.41) | 3.98 (3.48‐4.69) | 3.09 (2.71‐3.59) | 4.24 (3.71‐4.999) | 1.43 (1.32 to 1.55) | 1.48 (1.37 to 1.60) |
Abbreviations: ASIR, age‐standardized incidence rate; ASMR, age‐standardized mortality rate; EAPC, estimated annual percentage change; SDI, socio‐demographic index; CI, confidence interval; UI, uncertainty interval.