FIGURE 3.

Computational analysis and luciferase assay showed a direct binding between miR‐145 and MALAT1 (*P value < .05. vs MALAT1 + miR‐145 NC group). A, Candidate seed sequences of miR‐145 in the 3′UTR of MALAT1 as detected by computational analysis; B, Luciferase activity of KNS‐89 cells transfected with wild‐type or mutant MALAT1 and miR‐145 mimics or miR‐145 negative controls; C, Luciferase activity of SNB‐19 cells transfected with wild‐type or mutant MALAT1 and miR‐145 mimics or miR‐145 negative controls