Table 2.
Results of univariable and multivariable logistic regression analyses for individual high‐risk HPV genotypes/groups associated with cervical intraepithelial neoplasia grade 2 or greater (CIN2+)
| GeneXpert | Linear Array | |||
|---|---|---|---|---|
| Univariable odds ratio (95% CI) | Adjusted OR (95% CI) | Univariable odds ratio (95% CI) | Adjusted OR (95% CI) | |
| Women without HIV | ||||
| ANY | 51.991* (27.548‐98.121) | 36.168* (20.422‐64.052) | ||
| HPV16 | 27.993* (13.202‐59.356) | 64.532* (27.905‐149.232) | 24.491* (11.523‐52.052) | 44.516* (19.801‐100.081) |
| HPV18+ | 4.896* (2.285‐10.492) | 7.578* (2.789‐20.593) | ||
| 18 | 6.870* (2.338‐20.192) | 13.125* (3.864‐44.586) | ||
| 45 | 1.957 (0.543‐7.052) | 2.668 (0.510‐13.945) | ||
| HPV31+ | 12.578* (7.200‐21.971) | 25.745* (13.213‐50.166) | ||
| 31 | 9.044* (1.801‐45.402) | 26.968* (5.073‐143.361) | ||
| 33 | 7.475* (1.432‐39.030) | 21.310* (3.770‐120.442) | ||
| 35 | 16.273* (4.626‐57.239) | 39.039* (10.453‐145.797) | ||
| 52 | 6.284* (2.306‐17.130) | 13.515* (4.432‐41.212) | ||
| 58 | 5.525* (1.815‐16.819) | 12.988* (3.801‐44.384) | ||
| HPV51+ | 2.402 (0.926‐6.229) | |||
| 51 | 1.973 (0.688‐5.660) | |||
| 59 | 7.475* (1.432‐39.030) | |||
| HPV39+ | 2.176 (0.854‐5.540) | |||
| 39 | 0.962 (0.099‐9.336) | |||
| 56 | 2.898 (0.180‐46.683) | |||
| 66 | 0.720 (0.080‐6.500) | |||
| 68 | 1.751 (0.412‐7.437) | |||
| Women living with HIV | ||||
| ANY | 22.017* (11.413‐42.471) | 23.430* (12.399‐44.273) | ||
| HPV16 | 5.954* (3.375‐10.501) | 10.156* (5.269‐19.575) | 7.154* (3.927‐13.033) | 12.039* (6.143‐23.594) |
| HPV18+ | 2.529* (1.579‐4.051) | 2.709* (1.535‐4.781) | ||
| 18 | 2.409* (1.272‐4.564) | 3.143* (1.453‐6.801) | ||
| 45 | 2.041* (1.104‐3.774) | 2.274* (1.070‐4.831) | ||
| HPV31+ | 7.913* (5.112‐12.249) | 9.599* (5.885‐ 15.657) | ||
| 31 | 3.662* (1.250‐10.730) | 5.352* (1.525‐18.784) | ||
| 33 | 15.306* (4.545‐51.550) | 25.799* (7.169‐92.838) | ||
| 35 | 5.425* (2.845‐10.344) | 7.325* (3.499‐15.338) | ||
| 52 | 4.168* (1.691‐10.273) | 9.733* (3.617‐26.192) | ||
| 58 | 4.083* (2.144‐7.776) | 5.108* (2.393‐10.905) | ||
| HPV51+ | 1.981* (1.007‐3.899) | |||
| 51 | 2.150 (0.921‐5.019) | |||
| 59 | 1.616 (0.595‐4.389) | |||
| HPV39+ | 3.069* 1.801‐5.230 | |||
| 39 | 1.605 (0.458‐5.627) | |||
| 56 | 2.013 (0.533‐7.604) | |||
| 66 | 2.045 (0.791‐5.287) | |||
| 68 | 1.431 (0.541‐ 3.783) | |||
*
P < .05.