Table 1.
Clinical and biochemical characteristics (training cohort)
| Variable | CTRL [n = 30] | STEMI [n = 30] | SA [n = 38] | Overall P‐value | Pairwise comparisons | ||
|---|---|---|---|---|---|---|---|
| CTRL vs STEMI | CTRL vs SA | STEMI vs SA | |||||
| Age (y) | 60 ± 9.8 | 63 ± 12.5 | 65 ± 8.9 | .219 | – | – | – |
| Sex (ref. male) | 18 (60.0) | 24 (80.0) | 29 (76.3) | .176 | – | – | – |
| Familiarity for CAD (%) | 11 (36.7) | 6 (20.0) | 15 (39.5) | .201 | – | – | – |
| Hypertension (%) | 9 (30.0) | 13 (43.3) | 21 (55.3) | .114 | – | – | – |
| Diabetes (%) | 1 (3.3) | 4 (13.3) | 7 (18.4) | .165 | – | – | – |
| Dyslipidemia (%) | 12 (40.0) | 14 (46.7) | 21 (55.3) | .451 | – | – | – |
| CKD (%) | 2 (6.7) | 2 (6.7) | 1 (2.6) | .676 | – | – | – |
| Smoking Habit (%) | 2 (6.7) | 4 (13.3) | 8 (21.1) | .370 | – | – | – |
| Systolic BP (mm Hg) | 130 ± 14.1 | 134 ± 23.4 | 136 ± 17.2 | .523 | – | – | – |
| Diastolic BP (mm Hg) | 81 ± 5.0 | 82 ± 14.7 | 79 ± 8.2 | .714 | – | – | – |
| Weight (kg) | 75 ± 9.1 | 77 ± 14.9 | 79 ± 17.7 | .619 | – | – | – |
| BMI (kg/m2) | 26.4 ± 3.27 | 26.3 ± 4.25 | 27.3 ± 5.4 | .631 | – | – | – |
| hs‐troponin (ng/L) | 8 ± 11.1 | 669 ± 1295.0 | 10 ± 14.6 | .002 | .012 | 1.000 | .004 |
| WBC (n/L) | 7108 ± 2220.0 | 10 583 ± 2535.3 | 7439 ± 2244.9 | <.001 | <.001 | 1.000 | <.001 |
| Creatinine (mg/dL) | 0.89 ± 0.236 | 0.95 ± 0.196 | 0.94 ± 0.152 | .543 | – | – | – |
| GFR (mL/min) | 90 ± 14.3 | 88 ± 31.9 | 81 ± 29.8 | .490 | – | – | – |
| CRP (mg/L) | 1.8 ± 0.78 | 7.6 ± 7.30 | 5.0 ± 5.38 | .002 | .001 | .119 | .161 |
| Glycemia (mmol/L) | 6.6 ± 2.56 | 8.3 ± 2.98 | 7.2 ± 2.59 | .082 | – | – | – |
| Total cholesterol (mmol/L) | 4.8 ± 0.73 | 5.0 ± 1.47 | 4.5 ± 1.03 | .283 | – | – | – |
| HDL (mmol/L) | 1.4 ± 0.42 | 1.6 ± 1.66 | 1.3 ± 0.46 | .595 | – | – | – |
| Triglycerides (mmol/L) | 1.5 ± 1.18 | 1.5 ± 1.98 | 1.3 ± 0.65 | .805 | – | – | – |
| LVEF at echo (%) | 62 ± 4.3 | 52 ± 8.4 | 60 ± 7.0 | <.001 | <.001 | .614 | <.001 |
Clinical and biochemical characteristics of patients diagnosed with ST‐segment elevation myocardial infarction (STEMI; n = 30) compared to controls (CTRL; n = 30) and patients with stable angina (SA; n = 38), who were enrolled in the training cohort. Data are expressed as mean ± SD, or absolute number (percentage), when appropriated. P‐values < .05 were considered significant and indicated by bold characters.
Abbreviations: BP, Blood Pressure; CAD, Coronary Artery Disease; CKD, Chronic Kidney Disease; CRP, C‐Reactive Protein; GFR, Glomerular Filtration Rate; LVEF, Left Ventricular Ejection Fraction at echocardiography; WBC, White Blood Cells.