TABLE 3.
Sensitivity and specificity of AI‐assisted and manual cytology for detection of histologically confirmed cervical lesions a
| Sensitivity (95%CI) | Specificity (95%CI) | |||||||
|---|---|---|---|---|---|---|---|---|
| AI | Manual | Difference | P value | AI | Manual | Difference | P value | |
| CIN1+ | 88.9 (87.5‐90.3) | 82.1 (80.4‐83.8) | 6.8 (4.5‐9.0) | <.001 | 95.8 (95.6‐95.9) | 96.1 (95.9‐96.2) | −0.3 (−0.5 to −0.1) | <.001 |
| CIN2+ | 90.1 (88.3‐91.9) | 84.3 (82.1‐86.4) | 5.8 (3.0‐8.6) | <.001 | 94.8 (94.6‐94.9) | 95.2 (95.0‐95.3) | −0.4 (−0.2 to −0.6) | <.001 |
| CIN3+ | 90.9 (88.9‐92.8) | 86.4 (84.0‐88.8) | 4.5 (1.4‐7.5) | <.001 | 94.4 (94.3‐94.6) | 94.9 (94.7‐95.0) | −0.4 (−0.7 to −0.2) | <.001 |
Abbreviations: AI, artificial intelligence; CI, confidential interval; CIN, cervical intraepithelial neoplasia.
a
A total of 69 906 cases for sensitivity and specificity analyses, including 1907 CIN 1 to 3 grades, 4790 negative, and 63 209 women with normal cytology classified by both AI and manual cytology.