FIGURE 2.
Associations of genetically predicted serum insulin‐like growth factor‐1 (IGF‐1) levels with site‐specific cancers in Japanese individuals. Estimates were derived using the multiplicative random‐effects inverse‐variance weighted method and were based on 336 single‐nucleotide polymorphisms associated with IGF‐1 levels at the genome‐wide significance threshold and available in the BioBank Japan Project genome‐wide‐association study. 22 The I2 value is a measure of heterogeneity among estimates from individual single‐nucleotide polymorphisms