FIGURE 6.

Involvement of oestrogen in stressed female mice. (a) The plasma estrogen levels in female mice under stress conditions. The blood samples were collected at 0.5 h after exposure to novelty stress. n = 12 per group. (b) The effect of ovariectomy (OVX) on 1‐h food intake in control and stressed female mice. n = 9 per group. (c) Food intake at 1 h after exposure to novel stress in female mice. MPP (estrogen receptor (ER)‐α antagonist, 150 μg·kg⁻¹, i.p.) and PHTPP (ERβ antagonist, 150 μg·kg⁻¹, i.p.) were administered 2 h before stress exposure. n = 9 per group. Results are shown as means ± SEM. *P < 0.05 vs. each control; ^† P < 0.05 by the Tukey–Kramer test