Fig. 3.

Schematic illustration overview of post-translational modifications on other core clock proteins. Although post-translational modifications of PER2 are the most studied, other core clock proteins are also controlled by significant post-translational modification. Only the C-terminal tail of CRY2 is shown, but the high similarity between the CRY1 and CRY2 photolyase-homology region (PHR) likely means that post-translational events applicable to CRY1 also occur on CRY2. Owing to their large number, only selected CRY1 phosphosites are shown.