Table 2.

Side effects

Drug	Side effect
Hydroxychloroquine	Pruritus, anorexia, nausea, abdominal pain, blurring of vision, hypotension, QT prolongation -expectially in association with azithromycin, -hemolysis in G6PD-deficient, granulocytosis, anaphylactoid reaction, anaphylaxis, angioedema, alopecia, exfoliative dermatitis, ototoxicity, confusion, psychosis, seizures
Chloroquine	Retinopathy, anorexia, nausea, vomiting, headache, dizziness, blurred vision, QT prolongation
Azytromicin	diarrhea, nausea, vomiting, severe QT prolongation, abdominal pain
Lopinavir/Ritonavir	Prostration, anorexia, abdominal pain, diarrhea, nausea and vomiting, paresthesia, high level of AST, ALT, CK, pancreatitis, QT prolongation, headache, dyslipidemia, and taste alterations
Darunavir/cobicistat	Abdominal pain, prostration, anorexia, diarrhea, nausea and vomiting, rash, urticaria, Steven–Johnson syndrome, Drug Reaction with Eosynophilia and Systemic Symptoms, increased risk of bleeding in haemofiliac patients, reduction in eGFR (cobicistat), headhache, increase in liver enzymes, increase in fats levels, immune reconstitution syndrome
Remdesivir	Diarrhea, increase liver enzymes blood levels
Favipavir	Theratogenicity
Corticosteroids	Osteoporosis, osteonecrosis, hypertension, diabetes, fluid retention, cataracts and glaucoma, gastritits and gastric ulcera, increase risk of superinfection, neuropsychiatric adverse effects
Monoclonal antibodies	Tociluzumab: increased serious infections, reactivation of latent tuberculosis, headache, hypertension, hepatitis Eculizumab: hypertension, tachycardia, peripheral edema, hypotension, headache insomnia, fatigue, dizziness, skin rash, pruritus, hypokalemia, diarrhea, vomiting, nausea, abdominal pain, gastroenteritis, infection, life-threatening neisseria meningitides Sarilumab increased serum alanine aminotransferase, increased serum aspartate aminotransferase. Infection. Decreased platelet count, leukopenia, neutropenia Anakinra injection-site reaction, headache, vomiting, arthralgia, nasopharyngitis, nausea, fever, nausea, diarrhea, eosinophilia, decreased white blood cell count, change in platelet count