Table 4.

Quality of evidence and Grading of Recommendations Assessment Development and Evaluation (GRADE) recommendations for topical application of granulocyte macrophage colony stimulating growth factor in different types of wounds

Wound type	Quality of evidence	GRADE recommendation	References
Deep partial-thickness burns	High	Strong	80–86
Diabetic foot ulcers	Low	Weak	87,88
Chronic refractory wounds	Low	Weak	89