Table 1.

Drug interactions between commonly used medications in delirium and COVID-19 agents (adapted from Liverpool drug interactions group)

	ATZ	LPRT	REM	FAV	CHL	NIT	RIB	TOC
Haloperidol	↑♥	↑♥	↔	↔	↔♥	↔	↔	↔
Olanzapine	↔	↓	↔	↔	↔	↔	↔	↔
Risperidone	↑♥	↑♥	↔	↔	↑♥	↔	↔	↔
Quetiapine	↑♥	↑♥	↔	↔	↔♥	↔	↔	↔
Diazepam	↑	↑	↔	↔	↔	↔	↔	↔
Lorazepam	↔	↔	↔	↔	↔	↔	↔	↔
Midazolam	↑	↑	↔	↔	↔	↔	↔	↔

ATZ, atazanavir; LPRT, lopinavir/ritonavir; REM, remdesivir; FAV, favipiravir; CHL, chloroquine/hydroxychloroquine; NIT, nitazonide; RIB, ribavirin; TOC, tocilizumab.

↑ indicates potential for increased medication effects and ↓ indicates potential for decreased medication effects. ♥ indicates potential cardiac toxicity that may cause QT and/or PR prolongation.