Table 2.

KIR genotypes in normal individuals and IBD patients.

KIR genotype	KIR genes																				Patient (%)	Control (%)	P value	OR (95% CI)
	Inhibitory KIR										Activating KIR							Pseudogene
	2DL1	2DL2	2DL3	2DL4	2DL5	2DL5A	2DL5B	3DL1	3DL2	3DL3	2DS1	2DS2	2DS3	2DS4 F	2DS4 V	2DS5	3DS1	2DP1	3DP1-1	3DP1-2
Ulcerative colitis vs. control
1	+	+	+	+	+	+	+	+	+	+	+	+	−	−	+	+	+	+	+	+	3 (3%)	8 (3%)	0.97	1.0 (0.2-3.9)
2	+	−	+	+	+	+	−	+	+	+	+	−	−	−	+	+	+	+	−	+	8 (8%)	23 (9.2%)	0.95	0.4 (0.4-2.2)
3	+	+	+	+	+	+	+	−	+	+	+	+	+		−	+	+	+	−	+	2 (2%)	7 (2.6%)	0.76	0.8 (0.2-3.8)
Crohn's disease vs. control
1	+	+	+	+	+	+	+	+	+	+	+	+	−	−	+	+	+	+	+	+	3 (3.6%)	8 (3%)	0.75	1.2 (0.3-4.8)
2	+	+	+	+	+	+	+	+	+	+	+	+	+	−	+	+	+	+	−	+	2 (2.4%)	14 (5.4%)	0.31	0.46 (0.1-2.1)
3	+	−	+	+	+	+	−	+	+	+	+	−	−	−	+	+	+	+	−	+	5 (6%)	23 (9.2%)	0.48	0.69 (0.2-1.9)
4	+	+	+	+	+	+	+	−	+	+	+	+	+	−	−	+	+	+	−	+	4 (4.8%)	7 (2.6%)	0.30	1.9 (0.5-6.7)
5	+	−	+	+	+	+	−	+	+	+	+	−	+	−	+	−	+	+	−	+	5 (6%)	2 (0.7%)	0.01	8.7 (1.7-45.8)
6	+	+	+	+	+	+	+	+	+	+	+	+	+	−	+	−	−	+	−	+	9 (10.8%)	1 (0.4%)	0.001	33.2 (4.1-266.3)

A P value less than 0.05 was statistically significant. Genotype frequency less than 2% is not included. KIR: killer cell immunoglobulin-like receptor; CD: Crohn's disease; UC: ulcerative colitis.