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AST-mediated protection of RGCs detected by retrograde labeling. (a) Retrograde-labeled RGCs. Scale bars: 50 μm. (b) Quantification of retrograde-labeled RGCs. Note that the RGC number was significantly lower in Glast ±mice than in control mice, while loss of RGC was suppressed by 60 mg/kg/day AST administration. ∗∗P < 0.01. n.s.: not significant.
