Table 3.

Clinical scenarios needing the search of celiac disease in Sjögren syndrome patients or Sjögren syndrome in celiac disease patients

When to consider CD in SS patients?	When to consider SS in CD patients?
Suggestive gastrointestinal symptoms; Suspected malabsorption; Hypogammaglobulinemia and low levels of total protein; High levels of transaminases without evident cause; Anemia of unknown cause; Herpetiform dermatitis; Autoimmune thyroiditis (frequent in SS patients)[47]1	Dry eyes and dry mouth symptoms; Enlarged parotid glands; Hypergammaglobulinemia and high levels of total protein; Polyneuropathy; Arthritis (arthralgias?); Purpura

¹The National Institute for Health and Clinical Excellence guideline recommends that all patients with autoimmune thyroid disease must be screened for celiac disease. CD: Celiac disease; SS: Sjögren syndrome.