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. 2020 Sep 28;52(9):1627–1636. doi: 10.1038/s12276-020-00507-5

Fig. 5. Effect of oral administration of NZ-IL1Ra on DSS-induced colitis in model mice.

Fig. 5

a Schedule for colitis induction and oral administration. The in vivo experiment was repeated 3 times (total n = 18). b, c Change in body weight and DAI score, respectively, of mice with DSS-induced colitis. Data are the mean ± SE (n = 18). The p values of day 11 results are shown. d Colon length on day 11. Data are the mean ± SE (n = 12), and each dot in the plot represents one mouse. e, f Representative images of colon tissue stained with HE (10× magnification). e NZ–VC, f NZ-IL1Ra. g Total mucosal area on day 11. Data are the mean ± SE (n = 6), and each dot in the plot represents one mouse.