TABLE 3.

Analysis of the differential expression of 20 sRNAs between planktonic and biofilm conditions in standard Streptococcus mutans at 24 h

sRNAs	log2 Fold change (Biofilm/Planktonic)		Fold change (Biofilm/Planktonic)	t value	p‐value
sRNA0426	2.55	5.87		26.09	<0.001
sRNA0379	2.33	5.01		54.82	<0.001
sRNA0650	2.19	4.56		54.31	<0.001
sRNA0413	2.13	4.38		71.42	<0.001
sRNA0600	1.99	3.97		19.11	<0.001
sRNA0522	1.79	3.46		55.26	<0.001
sRNA0698	1.29	2.45		20.36	<0.001
sRNA0593	1.27	2.42		9.86	<0.001
sRNA0215	1.14	2.20		13.78	<0.001
sRNA0120	0.84	1.79		7.52	<0.001
sRNA0146	0.81	1.75		8.99	<0.001
sRNA0118	0.69	1.62		19.42	<0.001
sRNA0301	0.54	1.45		17.93	<0.001
sRNA0074	0.17	1.13		2.74	0.021
sRNA0329	−0.66	0.63		−7.43	<0.001
sRNA0187	−1.18	0.44		−13.44	<0.001
sRNA0330	−1.23	0.43		−12.83	<0.001
sRNA0679	−1.25	0.42		−15.81	<0.001
sRNA0250	‐	‐		‐	‐
sRNA0656	‐	‐		‐	‐

Expression of the 20 selected sRNAs under standard Streptococcus mutans biofilm conditions compared with planktonic conditions at 24 h. 18 sRNAs were differentially expressed between the two conditions; of these, sRNA0426 was the most significantly upregulated sRNA. The expression of sRNA0250 and sRNA0656 under these two conditions was not measured stably. The sequencing data for these sRNAs were obtained from (Zhu et al., 2018).