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Predicted B cell epitopes of the designed virus-like particle (VLP)-based vaccine. (A) Linear B cell epitopes based on the various physicochemical properties of the residues. The red boxes are related to the first and second fragments of hepatitis B surface antigen (HBsAg) inserted into hepatitis B core antigen (HBcAg). (B) Predicted discontinuous B cell epitopes for each monomer of the designed vaccine.
