Table 5.

Allelic distribution of analyzed genetic variants in migraine patients according to age of onset.

Age of Onset	< 10 Compare to ≥ 10 Years Old			< 15 Compare to ≥ 15 Years Old
-	p	OR	95% CI	p	OR	95% CI
SCN1A c.3199G>A G vs. A	0.0011	3.659	1.673-8.003	0.1448	0.6993	0.4348-1.125
SCN2A c.56G>A A vs. G	0.5036	0.6353	0.2058-1.962	0.4381	0.7319	0.3440-1.557
KCNK18 c.28A>G G vs. A	0.3459	0.5480	0.1156-2.598	0.3867	0.5517	0.1810-1.681
KCNK18 c.328T>C C vs. T	0.3028	0.2151	0.01136-4.071	0.6512	0.6563	0.09122-4.721
TRPA1 c.3053A>G G vs. A	0.0738	0.4476	0.1930-1.038	0.0199	1.883	1.130-3.138
STX1A c.31-1811C>T T vs. C	1.0000	1.046	0.4826-2.267	0.0076	1.895	1.183-3.034

SCN1A – sodium voltage-gated channel alpha subunit 1 gene, SCN2A – sodium voltage-gated channel alpha subunit 2 gene, KCNK18 – potassium channel subfamily K member 18 gene, TRPA1 – transient receptor potential ankyrin 1 gene, STX1A – syntaxin 1A gene.

Statistical significance at p<0.05, Fisher’s exact.