Table 3.
Independent prognostic factors (multivariate analysis).
| Characteristic | Disease-free survival | Cause-specific survival | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age (years) | ||||
| <60 | 1 | 1 | ||
| ≥60 | 2.41 (1.53–3.80) | <0.001 | 3.18 (1.34–7.57) | 0.009 |
| BMI (kg/m2) | ||||
| <30 | 1 | |||
| ≥30 | 0.22 (0.06–0.77) | 0.018 | ||
| Grade | ||||
| 1–2 | 1 | 1 | ||
| 3 | 2.39 (1.38–4.15) | 0.002 | 5.58 (2.45–12.7) | <0.001 |
| Myometrial invasion | ||||
| Inner half | 1 | 1 | ||
| Outer half | 1.79 (1.07–2.99) | 0.025 | 2.55 (1.05–6.20) | 0.038 |
| Cervical stromal invasion | ||||
| Absent | 1 | |||
| Present | 2.70 (1.48–4.95) | 0.001 | ||
| LVSI | ||||
| Absent | 1 | 1 | ||
| Present | 2.09 (1.25–3.50) | 0.005 | 3.43 (1.41–8.32) | 0.006 |
| Peritoneal cytology | ||||
| Negative cytology | 1 | 1 | ||
| Abnormal cytologya | 3.07 (1.81–5.23) | <0.001 | 3.42 (1.39–8.42) | 0.008 |
| Postop radiotherapy | ||||
| No | 1 | |||
| Yes | 1.88 (1.07–3.30) | 0.028 | ||
| Postop chemotherapy | ||||
| No | 1 | 1 | ||
| Yes | 0.52 (0.29–0.93) | 0.026 | 0.30 (0.13–0.72) | 0.007 |
Cox proportional hazard regression models for P-values. All the covariates with P < 0.05 on univariate analysis were entered in the initial model, and only the significant covariates with P < 0.05 in the final model are shown (conditional backward). Significant P-values are emboldened. Abbreviations: BMI, body mass index; LVSI, lympho-vascular space invasion; HR, hazard ratio; and CI, confidence interval.
a
Malignant or atypical cells on peritoneal cytology results.