Table 4.
Assessment of liver fat fraction during the follow-up period.
| Total ± completers) | VLCK diet | LC diet | ||
|---|---|---|---|---|
| (n = 39) | (n = 20) | (n = 19) | ||
| % Fat fraction (PDFF)** | Mean ± SD (95% CI) | Mean ± SD (95% CI) | Mean ± SD (95% CI) | pa |
| Baseline | 9.53 ± 6.7 (7.5) | 10.01 ± 6.74 (7.9) | 9.03 ± 6.8 (6.2) | 0.6554 |
| 2 months | 6.70 ± 5.06 (4.3) | 5.24 ± 3.81 (3.8) | 8.24 ± 5.82 (6.2) | 0.0634 |
| Difference | −2.83 ± 3.82 (−1.8) | −4.77 ± 4.26 (−3.4) | −0.79 ± 1.76 (−0.5) | 0.0006 |
| pb | — | <0.0001 | 0.0651 | |
| Liver steatosis* | n (%) | n (%) | n (%) | pc |
| Baseline | 26(66.7%) | 14(70%) | 12(63.2%) | 0.4547 |
| 2 months | 16 (41.0%) | 6 (30.0%) | 10 (52.6%) | 0.1509 |
| Improvement | 10 (25.6%) | 8 (40.0%) | 2 (10.5%) | 0.0351 |
| No improvement | 29 (74.4%) | 12 (60.0%) | 17 (89.5%) |
*
Liver steatosis = PDFF >5.4%.
**
PDFF = liver proton density fat fraction.
a
p-value for comparisons between groups among completers. Student unpaired-sample t-test.
b
p-value for comparisons between baseline and 2 months' follow-up for each group. Student paired-sample t-test.
c
p-value for comparisons between groups among completers χ2-test.