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. Author manuscript; available in PMC: 2020 Sep 28.
Published in final edited form as: Sci Transl Med. 2020 Jan 15;12(526):eaax6249. doi: 10.1126/scitranslmed.aax6249

Table 2.

Demographic information of recipients and the corresponding matched donors in relation to engraftment of donor-derived mutations.

Characteristic Category No donor mutation
(n = 14)
Mutation engrafted
(n = 11)
P Test performed
Donor age Median (range) 24 (21 to 39) 36 (20 to 58) 0.03 Wilcoxon rank-sum test
Donor gender Male 10 (71.4%) 8 (72.7%) 0.99 Fisher’s exact test
Female 4 (28.6%) 3 (27.3%)
Recipient age Median (range) 51 (27 to 65) 55 (19 to 69) 0.66 Wilcoxon rank-sum test
Recipient gender Male 13 (92.9%) 7 (63.6%) 0.13 Fisher’s exact test
Female 1 (7.1%) 4 (36.4%)
Primary disease AML/MDS 7 (50%) 9 (81.8%) 0.21 Fisher’s exact test
Non-AML 7 (50%) 2 (18.2%)
Disease status prior to transplant CR 7 (50%) 5 (45.4%)
Non-CR 7 (50%) 5 (45.4%) 0.99 Fisher’s exact test
Unknown 0 (0%) 1 (9.1%)
Conditioning MAC 8 (57.1%) 7 (63.6%) 0.99 Fisher’s exact test
Non-MAC 6 (42.9%) 4 (36.4%)
HLA mismatch No mismatch 13 (92.9%) 9 (81.8%) 0.56 Fisher’s exact test
Mismatch 1 (7.1%) 2 (18.2%)

CR, complete remission; MAC, myeloablative conditioning.