TABLE 4.
Multivariate Analysis of Factorsa Associated With Enrollment of AYAs (Aged 15–39 Years) onto Therapeutic and Nontherapeutic Cancer Studies
| Therapeutic |
Nontherapeutic |
|||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Race/ethnicityb | ||||
| White, non-Hispanic | - | NS | Referent | <.01 |
| African American | - | 0.38 (0.14–1.02) | ||
| Hispanic | - | 1.75 (1.12–2.72) | ||
| Asian/Pacific Islander | - | 1.80 (1.01–3.21) | ||
| Hospital | ||||
| Children’s hospital | Referent | <.01 | Referent | <.01 |
| Adult cancer hospital | 0.19 (0.08–0.41) | 0.06 (0.04–0.11) | ||
| Public hospital | 0.34 (0.20–0.59) | 0.10 (0.06–0.15) | ||
| Diagnosis | ||||
| Extracranial germ cell tumor | Referent | <.01 | Referent | <.01 |
| Lymphoma | 2.54 (1.01–6.42) | 0.98 (0.41–2.34) | ||
| Sarcoma | 1.72 (0.62–4.76) | 1.75 (0.77–3.98) | ||
| Acute leukemia | 3.86 (1.56–9.56) | 3.03 (1.43–6.39) | ||
| Breast carcinoma | 9.01 (3.77–21.56) | 44.37 (21.71–90.69) | ||
| Other | 1.04 (0.44–2.45) | 4.37 (2.29–8.33) | ||
Abbreviations: 95% CI, 95% confidence interval; AYAs, adolescents and young adults; NS, not significant; OR, odds ratio.
a
Age (as categorical variable, 5-year intervals), sex, race/ethnicity, hospital, and diagnosis.
b
Race/ethnicity was not found to be significantly associated with enrollment onto a therapeutic clinical trial.