TABLE 5.
Multivariate Analysis of Factorsa Associated With Enrollment of AYAs Restricted to Those Aged 15 to 21 Years onto Therapeutic and Nontherapeutic Cancer Studies
| Therapeutic |
Nontherapeutic |
|||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Hospital | ||||
| Children’s hospital | Referent | <.01 | Referent | <.01 |
| Adult cancer hospital | 0.22 (0.03–1.74) | 0.15 (0.05–0.45) | ||
| Public hospital | 0.26 (0.10–0.72) | 0.04 (0.01–0.11) | ||
| Diagnosisb | ||||
| Extracranial germ cell tumor | Referent | .05 | - | - |
| Lymphoma | 1.12 (0.23–5.53) | - | ||
| Sarcoma | 2.84 (0.69–11.76) | - | ||
| Acute leukemia | 2.38 (0.62–9.06) | - | ||
| Other | 0.71 (0.15–3.18) | - | ||
Abbreviations: 95% CI, 95% confidence interval; AYAs, adolescents and young adults; OR, odds ratio.
a
Age (as categorical variable, 5-year intervals), sex, race/ethnicity, hospital, and diagnosis (breast carcinoma excluded).
b
Diagnosis was not found to be significantly associated with enrollment onto a nontherapeutic clinical trial.