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. Author manuscript; available in PMC: 2020 Sep 28.
Published in final edited form as: Pediatr Blood Cancer. 2017 Oct 8;65(2):10.1002/pbc.26844. doi: 10.1002/pbc.26844

TABLE 3.

Participant outcomes in comparison to normative means

Measure Mean ± SD Range ≤16th percentile 17–84th percentile ≥85th percentile tb P Effect sizeb
n (%)
Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV)c n = 62
Verbal Comprehension Index 90.60 ± 11.41 65–124 20 (32.3) 40 (64.5) 2 (3.2) −6.49* <0.001 0.82
Perceptual Reasoning Index 96.35 ± 13.12 69–123 13(21.0) 44 (70.9) 5 (8.1) −2.19* 0.033 0.28
Working Memory Index 87.53 ± 10.25 68–116 23(37.1) 38 (61.3) 1 (1.6) −9.58* <0.001 1.22
Processing Speed Index 94.55 ± 12.73 62–126 18 (29.0) 41 (66.1) 3 (4.8) −3.34* 0.001 0.43
Wechsler Individual Achievement Test-Third Edition (WIAT-III)c n = 59
Reading Comprehension 95.02 ± 10.78 69–118 10(17.5) 45 (78.9) 2 (3.5) −3.49* 0.001 0.46
Numerical Operations 98.54 ± 13.49 67–129 10(16.9) 43 (72.9) 6(10.2) −0.08 0.410 0.11
Woodcock-Munoz Language Survey-Revised (WMLS-R)d n = 57
Broad English CALP 3.64 ± 0.65 2–5 3(5.2) 47 (82.5) 7 (12.3) 1.61 0.113 0.21
Conner's Continuous Performance Test (CPT-3)e n = 27
Omissions 51.85 ± 9.58 42–79 0 21 (77.8) 6(22.2) 1.01 0.324 0.19
Commissions 46.78 ± 6.70 35–57 7(25.9) 20 (74.1) 0 −2.50* 0.019 0.48
Hit Reaction Time 51.89 ± 9.17 37–79 3 (11.1) 19 (70.4) 5 (18.5) 1.07 0.294 0.21
Variability 50.85 ± 12.28 38–87 3(11.1) 20 (74.1) 4(14.8) 0.36 0.722 0.07
Preservations 49.30 ± 6.50 44–70 0 25 (92.6) 2 (7.4) −0.56 0.578 0.11
Hit Reaction Time Block Change 54.63 ± 12.85 20–87 1 (3.7) 18 (66.7) 8 (29.6) 1.87 0.072 0.36
Delis-Kaplan Executive Function System (D-KEFS)f n = 50–52
Color Word Inhibition 10.08 ± 2.20 5–15 6(11.5) 40 (77.0) 6(11.5) 0.25 0.802 0.03
Color Word Inhibition-Switching 9.90 ± 2.63 1–13 8 (15.7) 34 (66.7) 9 (17.6) −0.27 0.791 0.04
Trails Letter-Number Switching 8.54 ± 3.29 1–13 15 (30.0) 31 (62.0) 4 (8.0) −3.14* 0.003 0.44
The California Verbal Learning Test-Children's Version (CVLT-C)g n = 58
Trial 1 0.04 ± 1.05 −2.0 to 3.0 11 (19.0) 32 (55.2) 15 (25.8) 0.31 0.755 0.04
Trial 5 −0.26 ± 1.09 −3.5 to 2.0 20 (34.5) 26 (44.8) 12 (20.7) −1.81 0.076 0.24
Short Delay Free Recall 0.02 ± 0.84 −2.0 to 2.0 8(13.8) 38 (65.5) 12 (20.7) 0.16 0.876 0.02
Short Delay Cued Recall 0 ± 0.82 −2.0 to 1.5 9(15.5) 35 (60.3) 14(24.1) 0 1.000 0
Long Delay Free Recall 0.21 ± 0.80 −2.5 to 1.5 5 (8.6) 38 (65.5) 15 (25.8) 1.97 0.054 0.26
Long Delay Cued Recall 0.09 ± 0.80 −2.0 to 2.0 6(10.3) 39 (67.2) 13(22.4) 0.90 0.372 0.12
Discriminability 0.03 ± 0.77 −3.0 to 1.5 7(12.1) 45 (77.6) 6(10.3) 0.26 0.799 0.03
NEPSY-Second Edition (NEPSY-II)f n = 57–59
Memory for Designs 8.44 ± 2.78 3–15 22 (38.6) 31 (54.4) 4(7.0) −4.23* 0.56
Memory for Designs Delayed 9.44 ± 3.00 3–18 14 (24.6) 34 (59.6) 9 (15.8) −1.42 0.162 0.19
Behavior Rating Inventory of Executive Function (BRIEF) Parent Reporte n = 61–62
Behavioral Regulation Index 48.81 ± 9.15 36–80 10(16.1) 43 (69.4) 9 (14.5) −1.03 0.308 0.13
Working Memory Scale 56.55 ± 11.86 38–85 4(6.5) 36(58.1) 22 (35.5) 4.35* <0.001 0.55
Metacognition Index 53.51 ± 10.85 35–85 7 (11.5) 38 (62.3) 16(26.2) 2.53* 0.014 0.32
Behavior Rating Inventory of Executive Function (BRIEF) Teacher Reporte n = 35
Behavioral Regulation Index 47.74 ± 8.04 41–83 3 (8.6) 21 (60.0) 11 (31.4) −1.66 0.106 0.28
Working Memory Scale 54.86 ± 14.22 38–96 2 (5.7) 24 (68.6) 9(25.7) 2.02 0.051 0.34
Metacognition Index 53.26 ± 11.76 37–80 2 (5.7) 24 (68.6) 9 (25.7) 1.64 0.110 0.28
Behavior Assessment System for Children, Second Edition (BASC-2) Parent Reporte n = 61
Attention Problems 51.08 ± 10.23 35–75 12 (19.7) 33(54.1) 16(26.2) 0.83 0.412 0.11
Behavior Assessment System for Children, Second Edition (BASC-2) Teacher Reporte n = 36
Attention Problems 48.06 ± 9.46 37–69 11 (30.6) 19(52.8) 6 (16.7) −1.23 0.226 0.21
a

One-sample t-test comparing survivors to normative means.

b

Cohen’s d.

c

Mean = 100, SD = 15.

d

Mean = 3.5, SD = 0.5.

e

Mean = 50, SD = 10.

f

Mean = 10, SD = 3.

g

Mean = 0, SD = 1.

*

P < 0.05.