TABLE 1.
Mucins expression in different pancreatic neoplasms
| Normal | PanIN | Pancreatic cancer | Pancreatitis | IPMN | MCN | |||
|---|---|---|---|---|---|---|---|---|
| I | II | III | ||||||
| MUC1 | + | + | ++ | +++ | +++ | ++ | ± | ± |
| MUC2 | − | − | − | − | − | − | ++ | NA |
| MUC3 | ± | + | + | + | ++ | ± | ± | NA |
| MUC4 | − | + | ++ | +++ | +++ | − | ± | ++ |
| MUC5AC | − | + | ++ | +++ | +++ | ± | + | + |
| MUC5B | ± | NA | NA | NA | +++ | ++ | ± | NA |
| MUC6 | + | ++ | ++ | ++ | +++ | ++ | ++ | NA |
| MUC7 | NA | NA | NA | NA | + | + | NA | NA |
| MUC11/12 | ± | NA | NA | NA | NA | NA | NA | NA |
| MUC13 | ± | NA | NA | NA | +++ | NA | NA | NA |
| MUC16 | − | + | ++ | ++ | +++ | NA | NA | NA |
| MUC17 | + | ++ | ++ | ++ | + | NA | NA | NA |
| MUC20 | + | NA | NA | NA | NA | NA | NA | NA |
| MUC21 | + | NA | NA | NA | NA | NA | NA | NA |
Abbreviations: −, negative; +, low; ++, moderate; +++, intense; ±, negative or positive depending the reports; IPMN, intraductal papillary‐mucinous neoplasms; MCN, mucinous cystic neoplasm; NA, no available data; PanIN, pancreatic intra‐epithelial neoplasia.