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. 2020 Aug 6;24(18):10589–10603. doi: 10.1111/jcmm.15678

Figure 8.

Figure 8

Inhibition of CXCR7 prevented the recruitment and migration of circulating endothelial progenitor cells (EPCs). A and B, Representative flow cytometry histograms of isolated EPCs in kidneys and quantitative analysis of CD34+/CD133+/VEGFR2+ cells in the three groups. *P < .05 (IRI, LESW + IRI + CCX771 vs LESW + IRI). C, Representative fluorescence images of kidneys detected by in vivo imaging system. D, Quantitative analysis of the retention of the Dil‐C18(5)‐DS labelled circulating EPCs in kidney at 24 h after reperfusion in the three groups. E, The migrated ability of EPCs following stimulating with SDF‐1 (0‐200 ng/mL) without or with CCX771. Representative images were shown. F, Quantitative analysis of circulating EPCs migration. Scale bar = 50 μm. *P < .05 (10, 25, 50, 100, 200, 200 + CCX771 vs control and 0); + P < .05 (50, 100, 200 vs 10, 25, and 200 + CCX771); # P < .05 (100, 200 vs 50); & P < .05 (200 vs 100). LESW, low‐energy shock wave; SDF‐1, stromal cell–derived factor‐1