TABLE 2.
Genetic variants associated with HCC risk
| Genotype a | HCC (n = 280) | Control (n = 289) | OR (95%CI) | P value |
|---|---|---|---|---|
| rs75494098 (IVS2 + 135C>T) | ||||
| CC | 274 (97.9%) | 271 (93.8%) | 1.000 (Ref.) | .021 |
| CT/ TT | 6 (2.1%) | 18 (6.2%) | 0.330 (0.13‐0.84) | |
| Genotype a | HCC (n = 299) | Control (n = 299) | OR (95%CI) | P value |
|---|---|---|---|---|
| rs4721940 (IVS22‐123C > T) | ||||
| CC/ CT | 289 (96.7%) | 273 (91.3%) | 1.000 (Ref.) | .008 |
| TT | 10 (3.3%) | 26 (8.7%) | 0.363 (0.17‐0.77) | |
| Genotype a | HCC (n = 296) | Control (n = 299) | OR (95%CI) | P value |
|---|---|---|---|---|
| rs10254317 (2802G > A) | ||||
| AA/ AG | 277 (93.6%) | 262 (87.6%) | 1.000 (Ref.) | .014 |
| GG | 19 (6.4%) | 37 (12.4%) | 0.486 (0.27‐0.87) | |
Abbreviation: CI, confidence intervals; OR, odds ratios.
a
Genotypes of each SNP are arranged in descending order as homozygous dominant, heterozygous and homozygous minor alleles.