Table 1.

Associations between clinicopathological features and levels of GACAT3 and LNIC00152 in 406 CRC patients

Variables	GACAT3		P‐value	LINC00152		P‐value
	Low (n = 203)	High (n = 203)		Low (n = 203)	High (n = 203)
Gender
Male	121	113	.325	131	106	.012*
Female	79	90		72	97
Age (y)	59.5 ± 13.9	59.15 ± 12.5	.742	59.9 ± 13.5	58.6 ± 12.9	.302
BMI (kg/m2)	22.9 ± 3.2	22.8 ± 3.3	.733	22.8 ± 3.2	23.0 ± 3.2	.604
Morphological classification
Ulcerative type	125	134	.405	127	132	.586
Mass type	66	59		65	60
Depth of invasion
Tis	18	5	.016**	19	4	.018**
T1	10	7		7	10
T2	38	43		35	46
T3	60	81		70	71
T4	73	62		69	66
Differentiation
Poor	12	14	.782	13	13	.92
Intermediate/Well	167	174		167	174
Intestinal lymph nodes
0	106	112	.916	107	113	.989
1‐3	46	51		48	49
≥4	34	33		33	34
Lymph node metastasis
Negative	120	99	<.001***	118	101	.0038**
Positive	58	104		63	104
TNM
I‐II	134	100	<.001***	135	99	<.001***
III‐IV	69	103		68	104
CEA	10.6 (6.7‐14.4)	15.9 (6.0‐25.9)	.324	10.8 (6.6‐15.0)	16.9 (6.8‐3.9)	.27
CA19‐9	16.6 (14.2‐19.0)	33.7 (18.1‐43.3)	.0143*	20.2 (15.6‐24.9)	37.0 (21.2‐52.8)	.047*

Abbreviations: BMI, Body mass index; CA19‐9, Carbohydrate antigen 19‐9; CEA, Carcinoembryonic antigen; TNM, Tumor‐node‐metastasis.

^* P < .05.

^** P < .01.

^*** P < .001.