TABLE 1.

Correlation of PAK4, LIMK1 and Cofilin‐1 expressions with clinicopathological features of osteosarcoma

Clinicopathological features	No. of cases	PAK4 expression		P value	LIMK1 expression		P value	Cofilin‐1 expression		P value
		Positive	Negative		Positive	Negative		Positive	Negative
Age (year)				.494			.518			.772
>20	18	13	5		12	6		11	7
≤20	38	31	7		27	11		25	13
Gender				.732			.224			.382
Female	19	16	3		11	8		14	5
Male	37	28	9		28	9		22	15
Anatomic location				.744			.562			.413
Tibia/femur	32	26	6		21	11		19	13
Elsewhere	24	18	6		18	6		17	7
Tumor size				.189			.763			.143
≥8 cm	37	27	10		25	12		21	16
<8 cm	19	17	2		14	5		15	4
Clinical stage				.025			.040			.025
I‐IIA	30	20	10		17	13		15	15
IIB‐III	26	24	2		22	4		21	5
Metastasis				.039			.016			.021
Yes	20	19	1		18	2		17	3
No	36	25	11		21	15		19	17
Tumor grade				.040			.008			.003
Low	21	13	8		10	11		8	13
High	35	31	4		29	6		28	7