Table 2.
Clinco‐pathological items | Number of cases (n) | Univariate | P | Multivariate | P | ||
---|---|---|---|---|---|---|---|
HR | 95% CI | HR | 95% CI | ||||
Age (years old, n) | |||||||
<55 | 99 | ||||||
≥55 | 142 | 1.023 | 0.710‐1.472 | .904 | 0.99 | 0.687‐1.439 | .976 |
Gender (n) | |||||||
Male | 122 | ||||||
Female | 119 | 1.21 | 0.847‐1.729 | .296 | 1.21 | 0.841‐1.742 | .304 |
Histological type (n) | |||||||
Differentiated non‐keratinizing carcinoma | 21 | ||||||
Undifferentiated carcinoma | 220 | 1.032 | 0.540‐1.971 | .924 | 1.089 | 0.563‐2.106 | .800 |
Clinical staging (n) | |||||||
I‐II | 59 | ||||||
III‐IV | 182 | 1.857 | 1.137‐3.033 | .013 | 1.371 | 0.829‐2.269 | .219 |
Depth of infiltration (n) | |||||||
T1 + T2 | 109 | ||||||
T3 + T4 | 132 | 1.91 | 1.31‐2.785 | .001 | 1.76 | 1.194‐2.594 | .004* |
Lymph‐node metastasis (n) | |||||||
Yes | 185 | ||||||
No | 56 | 3.004 | 1.654‐5.456 | <.001 | 2.256 | 1.212‐4.201 | .010* |
Relative expression of hsa_circ_0028007 (n) | |||||||
Under‐expression | 160 | ||||||
Over‐expression | 81 | 2.55 | 1.605‐4.053 | <.001 | 1.738 | 1.067‐2.831 | .026* |
Abbreviations: CI, confidence interval; HR, hazard ratio.
Statistical significance.