Figure 5.

Single-Cell and Bulk RNA Sequencing of MAT from CD, UC, and H Reveals a Distinct Cellular Profile in CrF

(A) Bulk-RNA-sequencing-generated heatmap of differentially expressed genes (DEGs) in CrF versus H MAT. Genes with adjusted p value < 0.05 are shown.

(B) Fold change in expression level for a given gene in CrF versus H MAT, with adipose differentiation genes highlighted. Significant DEGs with adjusted p value < 0.05 are colored red.

(C) scRNA-seq-generated UMAP plots of CrF and H MAT distinguishing individual cell clusters (left) and tissue source (right). Frequency of cell types indicated by colored bars.

(D) scRNA-seq-generated UMAP plots of CrF and paired CD MAT distinguishing individual cell clusters (left) and tissue source (right). Frequency of cell types indicated by colored bars.

See also Figures S4 and Figure 1, Figure 2, Figure 3, Figure 4, Figure 5, Figure 6, Figure 7, Figure S1, Figure S2, Figure S3, Figure S4, Figure S5and Tables S6 and S7.