Table 2.

Demographic and clinical characteristics of COVID-19 patients who were positive for SARS-CoV-2 RNA in respiratory samples after admission.

Characteristics	Detection of SARS-CoV-2 RNA by NATe		p value
	Positive (N = 58)	Negative (N = 40)
Days from onset to admission, median (IQR)	4.0 (2.0–7.0)	6.0 (3.3–7.0)	0.086
Hospital stay, median days (IQR)	23.5 (17.0–28.0)	17.0 (13.3–23.8)	0.003
Days from onset to discharge, median (IQR)	28.0 (22.0–34.0)	25.0 (16.3–30.0)	0.050
Days of RNA sheddinga, median (IQR)	15.0 (12.0–19.0)	12.0 (9.0–14.8)	0.001
Anti-NP IgG seroconversion time, median days (IQR)	12.0 (9.0–15.0)	14.0 (10.8–16.3)	0.139
Anti-NP IgM seroconversion timeb, median days (IQR)	10.0 (5.5–19.0)	10.5 (9.0–12.0)	0.833
Anti-NP IgA seroconversion timeb, median days (IQR)	13.0 (5.5–22.5)	14.0 (9.0–15.0)	1.000
Age, median years (IQR)	55.0 (39.3–64.5)	46.0 (37.8–61.5)	0.231
Gender			1.000
Male	30 (51.7%)	20 (50.0%)
Female	28 (48.3%)	20 (50.0%)
Disease severity status			0.477
Severe	16 (27.6%)	8 (20.0%)
Mild/moderate	42 (72.4%)	32 (80.0%)
Positive nucleic acid test after admission
In blood samplec	1/7 (14.3%)	0	0.467
In anal swab sampled	16/53 (30.2%)	3/39 (7.7%)	0.009
Exposure history			0.075
Recently visited Hubei	36 (62.1%)	32 (80.0%)
Never been to Hubei	22 (37.9%)	8 (20.0%)
Symptoms
Fever	46 (79.3%)	31 (77.5%)	1.000
Cough	25 (43.1%)	20 (50.0%)	0.541

p values were calculated by Mann-Whitney U test, χ² test, or Fisher's exact test, as appropriate.

^aDays of RNA shedding was defined as intervals from illness onset through two consecutive throat-swab samples negative for SARS-CoV-2 RNA (at least 24 h apart), without converting positive thereafter.

^bIgM and IgA antibody against nucleocapsid proteins (NP) was tested on 15 patients.

^cBlood sample was collected from 15 patients for nucleic acid test.

^dAnal swab sample was collected from 92 patients for nucleic acid test.

^eNAT, nucleic acid testing.