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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Pain. 2020 Sep;161(Suppl 1):S65–S86. doi: 10.1097/j.pain.0000000000001922

Figure 3: A convergence of pathogenic mechanisms?

Figure 3:

There is accumulating evidence that the primary initiators of pathogenic cascades leading to diabetic neuropathy, impaired insulin signaling, hyperglycemia and dyslipidemia share a common pathway through disruption of mitochondrial bioenergetics.