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. 2020 Sep 4;46(5):1755–1764. doi: 10.3892/ijmm.2020.4720

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of miR-181b on human colon cancer cell proliferation. (A) Results of RT-qPCR showing miR-181b expression in cells. (B) Results of RT-qPCR showing miR-181b expression in cells following transfection. (C) Results of CCK-8 assay showing the cell proliferative ability. (D) Colony formation assay. (E) Transwell assay results showing cell invasion (magnification, ×400). (F) Transwell assay results showing cell migration (magnification, ×400). ^*P<0.05, compared with HCoEpiC cells or ^*P<0.05, compared with the BC group; ^#P<0.05, compared with the miR-181b group. BC, blank control; NC1, miR-181b overexpression negative control group; NC2, miR-181b silencing negative control group.