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. 2020 Sep 4;46(5):1755–1764. doi: 10.3892/ijmm.2020.4720

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of miR-181b targeting CYLD on SW480 cell xenografts. (A) Tumor volume. (B) Tumor image. (C) Tumor weight. (D) Immunohistochemistry results showing Ki67 expression in the transplanted tumors (magnification, ×400). (E) TUNEL assay results showing tumor cell apoptosis (magnification, ×400). (F) Results of western blot analysis showing the expression levels of the NF-κB signaling pathway-related proteins in tumor tissues. ^*P<0.05, compared with the BC group; ^{^}P<0.05, compared with the si-miR group; ^#P<0.05, compared with the CYLD group. BC, blank control; NC3, CYLD overexpression negative control; NC4, CYLD silencing negative control.