Table 1. GO and KEGG analysis of PD-1 co-expressing genes.
Term | Description | Count | P-value |
GO:0006955 | immune response | 20 | 2.03E-14 |
GO:0007165 | signal transduction | 13 | 0.005114 |
GO:0006954 | inflammatory response | 11 | 6.85E-06 |
GO:0002250 | adaptive immune response | 9 | 3.09E-07 |
GO:0033209 | tumor necrosis factor-mediated signaling pathway | 8 | 9.46E-07 |
GO:0050852 | T cell receptor signaling pathway | 8 | 4.31E-06 |
GO:0032496 | response to lipopolysaccharide | 7 | 9.14E-05 |
GO:0007166 | cell surface receptor signaling pathway | 7 | 0.001403 |
GO:0006915 | apoptotic process | 7 | 0.040946 |
GO:0031295 | T cell costimulation | 6 | 2.54E-05 |
hsa04060 | Cytokine-cytokine receptor interaction | 12 | 2.99E-07 |
hsa05340 | Primary immunodeficiency | 5 | 6.42E-05 |
hsa04514 | Cell adhesion molecules (CAMs) | 7 | 0.000292 |
hsa05321 | Inflammatory bowel disease (IBD) | 5 | 0.000763 |
hsa04640 | Hematopoietic cell lineage | 5 | 0.002395 |
hsa05323 | Rheumatoid arthritis | 5 | 0.002498 |
hsa04612 | Antigen processing and presentation | 4 | 0.013188 |
hsa04660 | T cell receptor signaling pathway | 4 | 0.027223 |
hsa04940 | Type I diabetes mellitus | 3 | 0.030529 |
hsa05168 | Herpes simplex infection | 5 | 0.030930 |