Table 2. Clinicopathological parameters of NSCLC patients with or without mutation/CNV of m6A regulatory genes.
With mutation and/or CNV* | Without mutation and CNV* | P-value | ||
Age | <=60 | 690 | 7 | 0.417 |
>60 | 255 | 29 | ||
gender | Female | 372 | 18 | 0.269 |
Male | 573 | 18 | ||
Pathological Stage | I | 479 | 22 | 0.363 |
II | 267 | 10 | ||
III | 157 | 3 | ||
IV | 32 | 0 | ||
Discrepancy | 10 | 1 | ||
T stage | T1 | 259 | 18 | 0.02 |
T2 | 536 | 11 | ||
T3 | 107 | 6 | ||
T4 | 41 | 1 | ||
TX | 2 | 0 | ||
N stage | N0 | 600 | 30 | 0.162 |
N1 | 218 | 3 | ||
N2 | 105 | 3 | ||
N3 | 7 | 0 | ||
Nx | 15 | 0 | ||
M stage | M0 | 709 | 23 | 0.078 |
M1 | 204 | 0 | ||
MX | 32 | 13 |
*With mutation or CNV: Cases have mutant or CNV or mutant+CNV, confirmed through TCGA database. Without mutant and CNV: Cases with neither mutant nor CNV, confirmed through TCGA database. Ambiguous variables (Nx, Mx, N/A, discrepancy and Gx) were excluded from chi-square test or non-parametric test.