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. 2020 Sep 9;12(17):17022–17037. doi: 10.18632/aging.103622

Table 3. Relationship between molecular characteristics and alteration of m6A regulatory genes in patients with NSCLC.

Without mutation or CNV* With mutation and CNV* X2 P
EGFR N=1017 wt 4 615 36.65 <0.0001
alteration 32 366
ERBB2 N=1017 wt 0 544 40.72 <0.0001
alteration 36 437
ALK N=1017 wt 0 459 28.84 <0.0001
alteration 36 522
KRAS N=1017 wt 5 547 22.87 <0.0001
alteration 31 434
MET N=1017 wt 2 573 37.36 <0.0001
alteration 34 408
TP53 N=1017 wt 1 672 64.11 <0.0001
alteration 35 309

*With mutation or CNV: Cases have mutant or CNV or mutant+CNV of m6A regulators, confirmed through TCGA database. Without mutant and CNV: Cases with neither mutant nor CNV of m6A regulators, confirmed through TCGA database.